Polyketides : biosynthesis, biological activity, and genetic engineering

by American Chemical Society. Meeting 2005 : San Diego, Calif.)

Format: Print Book 2007
Availability: Available at 1 Library 1 of 1 copy
Noncirculating (1)
Location Collection Call #
CLP - Main Library Second Floor - Closed Reference (Please ask for assistance) r QP752.P65 A44 2005
Location  CLP - Main Library
 
Collection  Second Floor - Closed Reference (Please ask for assistance)
 
Call Number  r QP752.P65 A44 2005
 
 
Summary
Polyketides represent an array of often structurally complex natural products produced by diverse organisms, many of which are pharmacologically valuable. This book provides an excellent overview of the chemistry, genetics, physiology, and enzymology of these compounds. The biosynthesis of polyketides represents a fascinating and dynamic area of investigation, and many new paradigms have recently emerged. The complexity of many of these molecules often renders their production via synthetic chemistry impractical; therefore an understanding of the chemistry and biology of systems producing these compounds will directly impact efforts toward the large scale industrial production of polyketides and polyketide-derivatives. The topics covered in this book range from the cloning and characterization of novel poyketide syntheses, structural and functional analysis of enzyme catalysis, the genetic engineering of new polyketide syntheses enzymes by rational design, and large-scale polyketide production strategies using heterologous systems. Academic and industrial leaders from around the world working in the fields of medicine, microbiology, and plant biology have included some of their latest results for this volume.
Additional Information
Series ACS symposium series ; 955.
Subjects Polyketides -- Congresses.
Publisher Washington, DC :American Chemical Society :2007
Distributed by Oxford University Press,
Contributors Rimando, Agnes M., 1957-
Baerson, Scott R.
American Chemical Society. Division of Agricultural and Food Chemistry.
Language English
Notes "Sponsored by the ACS Division of Agricultural and Food Chemistry, Inc."
"Developed from a symposium by the Division of Agricultural and Food Chemistry, Inc., at the 229th National Meeting of the American Chemical Society, San Diego, California, March 13-17, 2005"--Preface.
Description xii, 282 pages : illustrations ; 24 cm.
Bibliography Notes Includes bibliographical references and indexes.
ISBN 0841239789 (alk. paper)
9780841239784 (alk. paper)
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